**Core Concept**
Corpora amylacea are small, round, and homogeneous collections of amyloid, a type of protein. They are found in various tissues, particularly in the brain, kidneys, and liver, often associated with aging and certain pathological conditions.

**Why the Correct Answer is Right**
Corpora amylacea are formed due to the accumulation of amyloid protein, which is a fibrillar protein that can aggregate and deposit in tissues. In the context of the brain, this deposition can occur in the context of aging or as a result of neurodegenerative diseases such as Alzheimer's disease. The deposition of amyloid protein in the brain is thought to contribute to the pathogenesis of these diseases.

**Why Each Wrong Option is Incorrect**
**Option A:** Amyloidosis is a condition characterized by the deposition of amyloid protein in various tissues, but corpora amylacea are not a hallmark of amyloidosis.
**Option B:** Fatty change in the liver can lead to the accumulation of lipids, but it is not directly related to the formation of corpora amylacea.
**Option C:** Cerebral edema is a condition characterized by the accumulation of fluid in the brain, but it is not directly associated with the deposition of amyloid protein.

**Clinical Pearl / High-Yield Fact**
Corpora amylacea are a type of amyloid deposit that can be found in the brain, kidneys, and liver, often associated with aging and certain pathological conditions. They are a common finding in the brains of individuals over the age of 60.

**Correct Answer: C. Cerebral cortex**