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920 Skin

A 55-year-old woman complains to her physician that the skin of her armpits and groin “keeps getting darker and darker.” Physical examination demonstrates velvety brown and way skin in the axilla and groin. Biopsy of these lesions shows a variably hyperplastic epidermis with many sharp peaks and valleys. Aside from cosmetic considerations, which of the following is the primary medical significance of these lesions?

AThey may be a sign of immunosuppression
BThey may be a sign of visceral carcinoma
CThey may be easily superinfected
DThey may be malignant
Skin
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