Suppurating buboes are seen in infection with: March 2004
First, I need to recall what a bubo is. Buboes are swollen, tender lymph nodes, often associated with infections. When they're suppurating, that means they contain pus. So, which infections lead to suppurative (pus-filled) buboes?
Common causes of buboes include bacterial infections. For example, in the case of bubonic plague, caused by Yersinia pestis, the buboes are a hallmark. But are they suppurating? Wait, I think in plague, the buboes are more necrotic and not typically suppurating. They might become gangrenous instead.
Another possibility is gonorrhea. Neisseria gonorrhoeae can cause suppurative lymphadenitis, leading to buboes. If the infection spreads from the genital area, the lymph nodes in the groin might become inflamed and filled with pus.
Alternatively, tuberculosis can cause lymphadenitis, but those are usually non-suppurating and form caseous necrosis. Syphilis might also cause lymphadenopathy, but again, not typically suppurating.
Then there's lymphogranuloma venereum (LGV), caused by Chlamydia trachomatis. This can lead to suppurative buboes, especially in the later stages. The infection starts as a primary lesion, then the lymph nodes become involved, sometimes leading to suppurative and then fibrotic changes.
Wait, but the question is from March 2004. Maybe the options included C. trachomatis (LGV) or N. gonorrhoeae. Let me check standard references. In LGV, the buboes are suppurative and can rupture. In contrast, in bubonic plague, the buboes are not suppurative. So the correct answer here is likely Chlamydia trachomatis causing LGV, leading to suppurating buboes.
But wait, another possibility is in syphilis? No, syphilis is more of a non-suppurative lymphadenopathy. So the correct answer is LGV (Chlamydia). Let me confirm. Yes, LGV presents with suppurative buboes in the inguinal region. So if the options included Chlamydia trachomatis as the cause of LGV, that's the answer. Alternatively, maybe gonorrhea is another option. But I think LGV is more classic for suppurative buboes. So the correct answer is C. trachomatis (LGV).
**Core Concept**
Suppurating buboes are localized, pus-filled lymphadenitis typically caused by bacterial infections that spread via lymphatic channels. The etiology depends on the pathogen's tropism for lymph nodes and its ability to induce suppurative inflammation.
**Why the Correct Answer is Right**
*Chlamydia trachomatis* (Lymphogranuloma venereum, LGV) is a classic cause of suppurating buboes. The infection begins with a primary genital ulcer, followed by regional lymphadenopathy. The lymph nodes become tender, enlarge, and eventually suppurate due to necrotizing granul