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6958 Pharmacology

A patient of abdominal sepsis was staed on empirical treratment with intravenous ampicilling and gentamicin. Regarding the treatment of this patient, which statement is most accurate?

AEmpirical treatment of abdominal sepsis should always include a third generation cephalosporin
BA drug activbe against anaerobe should be included in the antibiotic regimen
CCombination of ampicillin and gentamicin provides good coverage for all likely pathogens
DIf the patient is severely allergic to ampicillin, then ceftriaxone should be used
Pharmacology
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6960 Pharmacology

A new diuretic is being studied in human volunteers. Compared with placebo, the new drug increases urine volume, decreases urinary Ca2+, increases body pH, and decreases serum K+. If this new drug has a similar mechanism of action to an established diuretic, it probably

Ablocks the NaCl cotransporter in the DCT
Bblocks aldosterone receptors in the CT
Cinhibits carbonic anhydrase in the PCT
Dinhibits the Na/K/2Cl cotransporter in the TAL
Pharmacology
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