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5434 Pharmacology

Drug X is normally administered to patients at a rate of 50 mg/hour. Elimination of the drug X from body takes place as: – Hepatic Metabolism 10% – Biliary Secretion 10% – Renal Excretion 80% This drug has to be administered to a 65 years old patient Uttaam Singh, with a GFR of 60 ml/min. (assuming normal GFR is 120ml/min). Liver and biliary functions are normal in this patient. What should be the dose rate of drug X in this patient?

A50 mg/hour
B30 mg/hr
C25 mg/hr
D100 mg/hr.
Pharmacology
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