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5373 Pharmacology

All of the following statements regarding bioavailability of a drug are true, EXCEPT:

AIt is the fraction of unchanged drug that reaches the systemic circulation
BBioavailability of an orally administered drug can be calculated by comparing the Area Under Curve after oral and intravenous (iv) administration of the drug
CLow oral bioavailability always and necessarily mean poor absorption (Correct Answer)
DBioavailability can be determined from plasma concentration or urinary excretion data.