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5277 Pharmacology

A female patient presented with depressed mood, loss of appetite and no interest in surroundings., There is associated insomnia. The onset of depression was preceeded by a history of business loss and soon after it she developed the following symptoms for the past one year. True statement regarding management patient is?

ANo treatment is necessary as it is due to business loss
BSSRI is the most efficacious of the available drugs
CStart SSRI treatment based on side effect profile
DCombination therapy of 2 anti-depressant drugs
Pharmacology
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5281 Pharmacology

Which one of the following statements best describes the mechanism of action of insulin on target cells ?

AInsulin binds to cytoplasmic receptor molecule and is transferred as a hormone receptor complex to the nucleus where it acts to modulate gene expression.
BInsulin binds to a receptor molecule on the outer surface of the plasma membrane and the hormone receptor complex activates adenylate cyclase through the Gs protein.
CInsulin binds to a transmembrane receptor at the outer surface of the plasma membrane, which activates the tyrosine kinase that is the cytosolic domain of the receptor.
DInsulin enters the cell and causes the release of calcium ions from intracellular stores.
Pharmacology
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