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7691 Pathology

A 60-year-old man, a heavy smoker, presents for advice to stop smoking. On physical examination, he is thin and has a ruddy complexion. He has a productive cough and a barrel-shaped chest. He sits leaning forward with his lips pursed to facilitate his breathing. A diagnosis of emphysema is made. Which of the following is the most likely histologic finding in the lungs?

ABronchial smooth muscle hyperophy with proliferation of eosinophils
BDiffuse alveolar damage with leakage of protein-rich fluid into alveolar spaces
CDilation of air spaces with destruction of alveolar walls (Correct Answer)
DHyperplasia of bronchial mucus-secreting submucosal glands