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7303 Pathology

A 68-year-old man has experienced increasing malaise for 3 years. Physical examination shows no remarkable findings. Laboratory findings include a serum creatinine level of 4.9 mg/dL and a urea nitrogen level of 45 mg/dL. Abdominal CT scan shows small kidneys. Which of the following endocrine glandular lesions has developed secondary to the underlying disease in this patient?

AAdrenal atrophy
BIslet cell hyperplasia
CMultinodular goiter
DParathyroid hyperplasia
Pathology
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7304 Pathology

A 40-year-old woman presents with an 8-month history of severe headaches, weakness, and dizziness. Blood pressure is 180/110 mm Hg. Physical examination shows diminished tendon reflexes. An abdominal CT scan reveals a 4-cm mass in the right adrenal gland. The results of laboratory studies include serum potassium of 2.3 mEq/L, serum sodium of 155 mEq/L, plasma cortisol of 25 mg/dL (8 AM) and 20 mg/dL (4 PM), and low plasma renin. These clinical and laboratory findings are consistent with an adrenal tumor that secretes which of the following hormones?

AAldosterone
BCortisol
CEpinephrine
DRenin
Pathology
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