Pathology MCQ Questions — Page 803

Question 1

A 58-year-old woman with colon cancer presents with 3 months of increasing shoness of breath. A chest X-ray reveals numerous, bilateral, round masses in both lungs. Histologic examination of an open-lung biopsy discloses malignant gland-like structures, which are nearly identical to the colon primary. Which of the following changes in cell behavior was the first step in the process leading to tumor metastasis from the colon to the lung in this patient?

Answer

Arrest within the circulating blood or lymph

Answer

Exit from the circulation into a new tissue

Answer

Invasion of the underlying basement membrane

Answer

Penetration of vascular or lymphatic channels

Question 2

AFGF

BTGF-a

CTGF-b

DPDGF

Question 3

DNone

Answer

Recurrent aboion

Answer

False +ve VDRL results

Answer

Increase prothrombin time

Question 4

APosterior

BInferior

Answer

Anterolateral

Answer

Subendocardial

Question 5

ALaminin 4

Answer

Collagen type 7

Answer

Alpha 6 integrin

Answer

Keratin 14

Question 6

ABreast

BLiver

CColon

DUterus

Question 7

DAll

Answer

Thrombocytopenia

Answer

Macroglobulinemia

Answer

Prothrombin time increased

Question 8

Answer

Alterations in the Aderoniatous Polypotis Coli (APC) / p-coctemia pathway are noted

Answer

They consist of proliferating malignant-appearing fibroblastic cells with abundant mitose

Answer

Primary modality of treatment is radiotherapy

Answer

They have a strong tendency to metastasize

Question 9

AT cell

BB cell

CNK cell

DMonocyte