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5824 Pathology

A 52-year-old man has a fever and cough productive of thick, gelatinous sputum that worsens over 4 days. On physical examination, his temperature is 38.2deg C. On auscultation of the chest, diffuse crackles are heard at the right lung base. Laboratory studies show WBC count, 13,240/mm3 with 71% segmented neutrophils, 8% bands, 15% lymphocytes, and 6% monocytes. A sputum gram stain shows gram-negative bacilli with mucoid capsules. His condition improves after a course of gentamicin therapy. Which of the following complications of this infection is he most likely to develop?

AAbscess formation
BAdenocarcinoma
CBullous emphysema
DCavitary granulomas
Pathology
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5829 Pathology

A 50-year-old man presents with a “staggering” gait and “lightning pain” in his hands and legs. His past medical history is significant for an aortic aneurysm and aortic insufficiency. Neurologic examination reveals impaired senses of vibration, as well as touch and pain in the lower extremities. The patient subsequently dies of pneumonia. Autopsy discloses obliterative endarteritis of meningeal blood vessels and atrophy of the posterior columns of the spinal cord. What is the appropriate diagnosis?

AAmyotrophic lateral sclerosis
BFriedreich ataxia
CHuntington disease
DTabes dorsalis
Pathology
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