A 52-year-old man has a fever and cough productive of thick, gelatinous sputum that worsens over 4 days. On physical examination, his temperature is 38.2deg C. On auscultation of the chest, diffuse crackles are heard at the right lung base. Laboratory studies show WBC count, 13,240/mm3 with 71% segmented neutrophils, 8% bands, 15% lymphocytes, and 6% monocytes. A sputum gram stain shows gram-negative bacilli with mucoid capsules. His condition improves after a course of gentamicin therapy. Which of the following complications of this infection is he most likely to develop?
A 52-year-old man has a fever and cough productive of thick, gelatinous sputum that worsens over 4 days. On physical examination, his temperature is 38.2deg C. On auscultation of the chest, diffuse crackles are heard at the right lung base. Laboratory studies show WBC count, 13,240/mm3 with 71% segmented neutrophils, 8% bands, 15% lymphocytes, and 6% monocytes. A sputum gram stain shows gram-negative bacilli with mucoid capsules. His condition improves after a course of gentamicin therapy. Which of the following complications of this infection is he most likely to develop?
π‘ Explanation
**Core Concept**
The patient is presenting with symptoms of a respiratory infection, likely pneumonia, given the fever, cough with thick sputum, and diffuse crackles at the lung base. The presence of gram-negative bacilli with mucoid capsules in the sputum gram stain is indicative of a specific type of bacterial infection.
**Why the Correct Answer is Right**
The patient's symptoms and laboratory findings, including the sputum gram stain showing gram-negative bacilli with mucoid capsules, are consistent with **Klebsiella pneumoniae** infection. This bacterium is known for causing severe pneumonia, particularly in individuals with underlying health conditions or compromised immune systems. The improvement with gentamicin therapy, an antibiotic effective against gram-negative bacteria, further supports this diagnosis.
**Why Each Wrong Option is Incorrect**
**Option A:** This choice is incorrect because it does not directly relate to the common complications of **Klebsiella pneumoniae** infection.
**Option B:** Similarly, this option does not align with the typical complications associated with this infection.
**Option C:** This choice is also incorrect as it is not a direct consequence of the described infection.
**Option D:** This option is not relevant to the expected complications of **Klebsiella pneumoniae** pneumonia.
**Clinical Pearl / High-Yield Fact**
A key point to remember is that **Klebsiella pneumoniae** infections can lead to severe complications, including abscess formation and bacteremia, due to the virulence of the bacterium and its mucoid capsule, which enhances its ability to cause disease.
**Correct Answer:** D. Abscess formation
β Correct Answer: A. Abscess formation
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