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5178 Pathology

70 year old male presented with 3-months history of generalised weakness. On examination, bilateral axillary lymphadenopathy was noted. Histopathological examination of enlarged lymph node showed effacement of lymph node architecture by diffuse proliferation of small-sized, mature-appearing lymphoid cells. Peripheral blood showed lymphocytosis with presence of CD5-positive and CD23-positive B-cells. Which of the following is the most likely diagnosis of this patient?

ABurkitt leukemia
BHodgkin lymphoma
CChronic lymphocytic leukemia (CLL)
DDiffuse large B-cell lymphoma (DLBCL)
Pathology
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5183 Pathology

A 7-year-old child has had worsening performance in school for the past 4 months from decreased vision. Examination of the right eye shows diffuse punctate inflammation of the cornea and pannus extending as growth of fibrovascular tissue from conjunctiva onto the cornea. Microscopic examination of a corneal scraping shows lymphocytes, plasma cells, neutrophils, and scattered corneal epithelial cells that have cytoplasmic inclusion bodies. Which of the following infectious agents is most likely to produce these findings?

AChlamydia trachomatis
BCytomegalovirus
CHerpes simplex virus
DRubella virus
Pathology
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