Mcq Subject: Pathology

A study of patients more than 25 years of age with body mass index above 30, dyslipidemia, hypertension, and fasting glucose averaging 115 mg/ dL is performed. They have adipose tissue abnormalities including increased non-esterified fatty acid release, altered adipokines with decreased adiponectin, greater proinflammatory cytokine release, and diminished peroxisome proliferator-activated receptor gamma (PPARg) function. Which of the following is the best initial therapeutic intervention for these patients?

A. Adrenalectomy

B. Caloric restriction

C. Insulin injection

D. L-Thyroxine

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Which of the following mutation seen in Cowden syndrome?

A. PTCH mutation

B. PTEN mutation

C. STK11 mutation

D. SMAD4 mutation

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A 62-year-old man presents with pallor, fatigue, and dyspnea on exeion. A complete blood count reveals microcytic hypochromic anemia. The likely cause of this hematological finding is?

A. Increased iron requirement

B. Gastrointestinal bleeding

C. Hypersplenism

D. Hemolytic anemia

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In which of the following conditions is negative nitroblue tetrazolium dye test result seen?

A. Tuberculosis

B. Chronic granulomatous disease

C. Severe combined Immunodeficiency

D. DiGeorge syndrome

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Which among the following is not a copper deficiency disease:

A. Hunter's disease.

B. Wilson's disease.

C. Menke's syndrome.

D. Hepatolenticular degeneration.

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Cells seen in MI at 48 hours are

A. polymorphs

B. Fibroblasts

C. Lymphocytes

D. Macrophages

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Which one of the following gross appearances of a kidney is most characteristic of malignant nephrosclerosis?

A. Broad U-shaped coical scars overlying dilated calyces in renal poles

B. Depressed coical areas overlying necrotic papillae of varying stages

C. Multiple small petechial hemorrhages on the surface

D. Multiple small white areas on the surface

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Pendred syndrome due to mutation of ?

A. Baillin

B. Pendrin

C. Fibrillin

D. Reticulin

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Rind sign is seen:

A. Marfan syndrome.

B. Osteopetrosis.

C. Fibrous dysplasia.

D. All of the above.

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Most common type of hypopharyngeal carcinoma is?

A. Adenocarcinoma

B. Lymphoma

C. SCC

D. Neuro-endocrine tumor

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