Mcq Subject: Pathology

In alcoholic liver disease, which of the following pigments deposited in the hepatocytes –

A. Hemosiderin

B. Hemoglobin

C. Lipofuscin

D. Melanin

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The swollen degenerating epithelial cell due to acantholysis is:

A. Tzanck cell.

B. Ghost cell.

C. Prickle cell

D. Anitschow cell

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ATRA is used in treatment of tumour which is associated with which of the following

A. PML RARA

B. BCR ABL

C. C myc

D. CEBPA

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Most specific histological lesion in diabetic nephropathy is –

A. Glomerular crescents

B. Immune complex deposition

C. Occlusion of glomeruli with fibrin caps

D. Nodular glomerulosclerosis

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Hutchinson’s secondaries in skull are due to tumors in which of the following organs?

A. Lungs

B. Breast

C. Liver

D. Adrenals

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Known Associations of Coeliac disease include the following except

A. Epilepsy with posterior cerebellar calcification

B. IgA nephropathy

C. Oesophageal carcinoma

D. Addison's disease

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A 50-year-old woman develops a sudden, severe headache and is taken to the emergency department. On examination, she has nuchal rigidity. Her blood pressure is 115/83 mm Hg. A lumbar puncture is done; the CSF shows numerous RBCs, no neutrophils, a few mononuclear cells, and a normal glucose level. The Gram stain result is negative. CT imaging shows subarachnoid hemorrhage at the base of the brain. Which of the following vascular events has most likely occurred in this woman?

A. Bleeding from cerebral amyloid angiopathy

B. Hematoma formation from arteriolosclerosis

C. Middle cerebral artery thromboembolism

D. Rupture of an intracranial berry aneurysm

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A 36-year-old, alcoholic woman presents with a 1-week history of yellow skin and sclerae. She has suffered persistent headaches. Her vital signs are normal. Physical examination reveals jaundice. Laboratory studies disclose markedly elevated levels of AST and ALT (956 and 1,400 U/L, respectively). A few days later, she develops hepatic encephalopathy and renal failure. A liver biopsy shows prominent centrilobular necrosis. Which of the following is the most likely diagnosis?

A. Acetaminophen toxicity

B. Fatty liver of pregnancy

C. Metastatic carcinoma

D. Reye syndrome

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Alpha thalassemia is due to ?

A. Alpha chain deficiency

B. Alpha chain excess

C. Beta chain deficienc

D. Beta chain excess

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A 24 year old male presented with retroperitoneal left necrotic mass near the hilum of kidney which showed heterogenous contrast enhancement on CECT. What is the probable diagnosis?

A. Metastatic transitional cell carcinoma

B. Metastatic melanoma

C. Metastatic germ cell tumour

D. Lymphoma

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