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9321 Microbiology

A 35-year-old male patient presents with numerous subcutaneous hemorrhages. History and physical examination reveal that he has been taking sedormid (a sedative) for the past week. Laboratory tests indicate normal hemoglobin and white blood cell levels with significant thrombocytopenia (very low platelet count). You suspect that he has developed a drug-induced type II hypersensitivity reaction. This reaction may occur if the drug does which of the following?

AActivates T cytotoxic cells
BActs as a hapten
CInduces mast cell degranulation, releasing mediators such as histamine, leukotrienes, and prostaglandins
DInduces oxygen radical production through the respiratory burst pathway
Microbiology
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