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11793 Medicine

An anesthetized patient is mechanically ventilated at her normal tidal volume but at twice her normal frequency. When mechanical ventilation is stopped, the patient fails to breathe spontaneously for 1 minute. This temporary cessation of breathing occurs because

AThe elevated aerial oxygen tension (Pao2) reduced peripheral chemoreceptor activity
BThe elevated (Pao2) reduced central chemoreceptor activity
CLow levels of nitrogen are known to inhibit ventilation
DThe lowered carbon dioxide tension (Pao2) reduced central chemoreceptor activity
Medicine
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11798 Medicine

A 33-year-old lady presents with polydipsia and polyuria. Her symptoms started soon after a road traffic accident 6 months ago. The blood pressure is 120/80 mm Hg with no postural drop. The daily urinary output is 6-8 litres. Investigation showed, Na 130 mEq/L, K.3.5 mEq/L, urea 15mgAIL, sugar-65 mg/dL. The plasma osmolality is 268 mosmoUL and urine osmolality 45 mosmol/L. The most likely diagnosis is –

ACentral diabetes insipidus
BNephrogenic diabetes insipidus
CResolving acute tubular necrosis
DPsychogenic polydipsia
Medicine
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