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4298 Biochemistry

A four-year-old child is diagnosed with Duchennemuscular dystrophy, an X-linked recessive disorder. Genetic analysis shows that the patient’s gene for the muscle protein dystrophin contains a mutation in its promoter region. What would be the most likely effect of this mutation?

ATailing of dystrophin mRNA will be defective
BCapping of dystrophin mRNA will he defective.
CTermination of dystrophin transcription will be deficient.
DInitiation of dystrophin transcription will be deficient. (Correct Answer)