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A 40-year-old man presented with history of episodic palpitations and headaches. The patient was fine until 1 year back when the patient staed experiencing spells of rapid heabeat. These became more severe and were eventually accompanied by throbbing headaches and drenching sweats. Physical examination revealed a blood pressure of 154/94 mm Hg and hea rate of 86 bpm. During the physical examination, palpation of the abdomen elicited a sudden and typical episode, with a rise in blood pressure to 214/128 mm Hg, hea rate to 128 bpm, profuse sweating, and facial pallor. This was accompanied by severe headache. MRI and PET SCAN is given below. Which of the following is true regarding the patient's condition?
10% of these tumours are unilateral
24-hour urinary excretion of VMA is the most sensitive test to diagnose this condition.
Histopathologically, the tumor consists of clusters of polygonal or spindle shaped chromaffin cells suppoed by sustentacular cells in a nest like pattern.
Phenoxybenzamine is a reversible alpha blocker, hence used in the challenge test to diagnose this condition.
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