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A 45-year-old male patient presented to the medicine OPD with the chief complaints of progressive forgetfulness over the past few years along with ataxia. O/E, Wide based shuffling gait Generalized rigidity Hyperextension of neck On examination of eye Restricted eye movements Slow ocular saccades impairment of downward gaze MRI brain Which protein will be deposited most commonly in the subcoical structures in the above condition: -
Tau
Beta-syn-nuclein
Gamma-syn-nuclein
Amyloid-beta
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