Unknown

A 56 year old lady comes to medicine OPD with chief complains of headache, dizziness and generalized itching paicularly after taking hot shower. She also complained of intense burning in hands and feet as shown. She repos that taking aspirin relieves her of this issue. Physical examination: splenomegaly with raised BP. Blood workup shows: HB- 20.1 g/dl Hematocrit-60-% WBC-15800 platlet count- 500000 EPO- low spO2 - 98% LAP- increased. The patient was diagnosed with JAK2V617F mutation. Which of the following HPE slides correspond to above clinical condition?