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Surgery
A 40 year old woman has severe, disabling rheumatoid ahritis. Rheumatoid factor is positive. What would a biopsy of the synovium of her knee most likely reveal?
A nearly normal synovium with scattered inflammatory cells
A non-proliferative synovitis with abscess formation
A non-proliferative synovitis with many neutrophils
A proliferative synovitis with many lymphocytes, macrophages, and plasma cells
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