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Physiology
A 17-year-old soccer player suffered a fracture to the left tibia. After his lower leg has been in a cast for 8 weeks, he found that the left gastrocnemius muscle is significantly smaller in circumference than it was before the fracture. What is the most likely explanation?
Decrease in the number of individual muscle fibers in the muscle.
Decrease in blood flow to the muscle caused by constriction from the cast.
Temporary reduction in actin and myosin protein synthesis
Progressive denervation.
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