99% virions, a small number survive within the resting CD4 lymphocytes and invariably give rise to relapse when treatment is discontinued despite complete absence of detectable viraemia and normal CD4 cell count for years. Lipodystrophy and metabolic complications Lactic acidosis Myelosuppression. Hypersensitivity rash Hepatotoxicity. Neuropsychiatric disorders. stavudine-induced peripheral neuropathy didanosine-induced pancreatitis fatigue with conjunctival pallor (due to zidovudine-related anemia), and peripheral wasting (due to stavudine-related lipodystrophy) ESSENTIALS OF MEDICAL PHARMACOLOGY,en.wikipedia.org, www.who.int/topics/antiretroviral_topics/en/ K.D.TRIPATHI SIXTH EDITION PAGE NO:774">