Pharmacology

Which of the follwing statements regarding drugs used in leprosy is FALSE?

Single intramuscular injections of acedapsone maintain inhibitory levels of dapsone in tissues for upto 3 months

Monthly doses of rifampicin delay the emergence of resistance to dapsone

Clofazimine should not be given to patients who are intolerant to dapsone or who fail to improve during treatment with dapsone

Clofazimine may cause changes in the skin colour