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Pharmacology
A 47-year-old woman presents with complaints of nervousness and increased sensitivity to hot weather. She is diagnosed with hypehyroidism and prescribed propylthiouracil. What is the principal mechanism by which this drug acts?
Decreasing the efficacy of TSH binding to the thyroid TSH receptor
Decreasing the rate of proteolysis of thyroglobulin
Increasing the amount of 3,3',5'-triiodothyronine (reverse T3; rT3)
Inhibiting deiodination of thyroxine (T4)
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