Pharmacology

Which one of the following statements about the management of patients with GI ulcers is accurate?

Overall, H2 receptor blockers are as effective as proton pump inhibitors.

Antimicrobial regimens that eradicate Helicobacter pylori are >98% effective in GI ulcers.

Omeprazole is effective because it activates PGE1 receptors.

Sucralfate polymerizes in the gut, forming a protective coat over ulcer beds.