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Pharmacology
Which of the following statements about the fluoroquinolones is FALSE?
Gonococcal resistance to fluoroquinolones may involve changes in DNA gyrase
Modification of fluoroquinolones dosage is required in patients if creatinine clearance is less than 50 mL/min
A fluoroquinolone is the drug of choice for treatment of an uncomplicated urinary tract infection in a 7 year-old girl
Fluoroquinolones inhibit relaxation of positively supercoiled DNA
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