Pharmacology

Regarding the antibacterial action of gentamicin, which of the following statements is most accurate?

Efficacy is directly propoionate to the time that the plasma level of the drug is greater than the minimal inhibitory concentration

Gentamicin continues to exe antibacterial effects even after plasma levels decrease below detectable range

Antibacterial activity is often reduced by the presence of an inhibitor of cell wall synthesis

The antibacterial action of gentamicin is time dependent