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Pediatrics
Physical examination of a neonate is remarkable for a holosystolic murmur. There is no cyanosis.Echocardiography demonstrates an ostium primum defect in the lower pa of the interatrial septum that is accompanied by malformations of the adjacent atrioventricular valves. These lesions are most likely associated with which of the following disorders?
Cystic fibrosis
Down syndrome
Gaucher disease
Marfan syndrome
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