90% of patients, and returns to normal 6-8 wk after onset. C4 is most often normal. Serum CH50 is commonly depressed A biopsy is rarely indicated when: renal function is severely impaired beyond 7-10 days serum C3 remains depressed beyond 12 weeks Patient with features of a systemic illness Management of PSGN involves: Symptomatic & suppoive therapy (treating the acute effects of renal insufficiency and hypeension)">