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Pathology
Which one of the following statements about Hemoglobin S (HbS) is not true -
Hemoglobin HbS differs from hemoglobin HbA by the substitution of Val for Glu in position 6 of the beta chain
One altered peptide of HbS migrates faster towards the cathode (-) than the corresponding peptide of HbA
Binding of HbS to the deoxygenated HbA can extend the polymer and cause sickling of the red blood cells
Lowering the concentration of deoxygenated HbS can prevent sickling
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