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Pathology
A 90-year-old woman with mild diabetes and Alzheimer's disease die in her sleep. At autopsy, hepatocytes are noted to contain golden cytoplasmic granules that do not stain with Prussian blue. Which of the following best accounts for pigment accumulation in the liver of this patient?
Advanced age
Alzheimer disease
Congestive hea failure
Diabetic ketoacidosis
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