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Pathology
A 66-year-old woman dies of severe congestive hea failure. Her past medical history is remarkable for rheumatoid ahritis that first manifested at the age of 35. The autopsy revealed splenomegaly, hepatomegaly, and glomerulopathy. The spleen, liver, and kidneys showed a similar waxy texture. Which of the following mechanisms explains these clinical and pathologic findings?
Accumulation of amyloid
Atherosclerosis of coronary aeries
Coxsackievirus myocarditis
Mutation of myosin chain genes
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