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Pathology
A 50-year-old man dies of a respiratory illness that had been characterized by dyspnea, cough, and wheezing expiration of many years' duration. Initially episodic, his "attacks" had increased in frequency and at the time of death had become continuous and intractable. At autopsy, which of the following is the most likely histologic finding in the lungs?
Bronchial smooth muscle hyperophy with proliferation of eosinophils
Diffuse alveolar damage with leakage of protein-rich fluid into alveolar spaces
Dilation of air spaces with destruction of alveolar walls
Hypoplasia of bronchial mucus-secreting submucosal glands
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