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Pathology
A 54-year-old man, a nonsmoker, has a nonhealing ulceration at the base of his tongue on the right side for 2 months. On examination this lesion is 1 cm in diameter with irregular borders. Biopsy of the lesion is performed and microscopic examination shows infiltrating squamous cell carcinoma. Which of the following infectious agents is most likely to be associated with this lesion?
Candida albicans
Herpes simplex virus (HSV)
Human papillomavirus (HPV)
Prevotella intermedia
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