Pathology

A 63-year-old man has had progressively worsening dyspnea over the past 10 years. He has noticed a 5-kg weight loss in the past 2 years. He has a chronic cough with minimal sputum production and no chest pain. On physical examination, he is afebrile and normotensive. A chest radiograph shows extensive interstitial disease. Pulmonary function tests show diminished DLCO, low FVC, and normal FEV1/FVC ratio. Increased exposure to which of the following pollutants is most likely to produce these findings?