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Pathology
A 25-year-old man presents with low grade fever, weight loss, fatigue, crampy abdominal pain, episodic diarrhea & postprandial bloating. Right lower quadrant tenderness is elicited on palpation of abdomen. A capsule endoscopy reveals thickening of terminal ileum, edema, marked luminal narrowing, and a cobblestone appearance of the mucosa. Which of the following is a characteristic of this condition?
Additional typical findings include crypt abscesses and pseudopolyps.
Inflammation and ulceration limited to mucosa and submucosa with sparing of deeper layers.
It can affect any poion of the gastrointestinal tract, but proximal jejunum is most common site of involvement.
It can cause fistula formation between loops of affected bowel.
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