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Microbiology
A superantigen is a bacterial product that -
Binds to B7 and CD28 costimulatory molecules
Binds to the beta chain of TCR and MHC class II molecules of APC stimulating T cell activation
Binds to the CD4+ molecule causing T cell activation
Is presented by mactrophages to a larger-than-normal number of T helper CD4 + lumphocytes
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