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Microbiology
An infant with a history of delayed separation of umbilical cord now presents with recurrent pneumonia. The total count is 20,000/ml. Which of the following genetic defects is most likely present?
Low levels of NADPH oxidase and negative DHR test
Mutation of Bruton tyrosine kinase gene
Excessive IgM with reduced IgG and IgA
Reduced phagocyte surface expression of Sialyl-Lewis x
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