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Microbiology
A 45 yr old male presents with fever, cough, and anorexia. Sputum is positive for AFB. He is staed on isoniazid, rifampicin, pyrazinamide and ethambutol. What is the reason for administering multidrug therapy in tuberculosis?
To broaden antimicrobial spectrum
To delay development of resistance
To prevent toxin release from the organism
To reduce toxicity
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