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Microbiology
Twelve elderly residents living in an assisted care facility suffered from sinusitis, otitis media, and mild pneumonias during midwinter. Despite the fact that they had all received the 13-valent pneumococcal conjugate vaccine recently licensed for adults, S. pneumoniae was isolated from 10 of the patients. Which of the following is the best explanation for the pneumococcal infections?
Elderly patients do not mount good immune responses to vaccines
Some patients will not respond to the vaccine
The capsular type responsible was not present in the vaccine
The vaccine was defective
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