Non-Jewish Caucasian > African American > Hispanic > AsianJewish > Non-Jewish Caucasian > African American > Hispanic > AsianMale: Female ratio1:11.1--1.8:1SmokingMay prevent diseaseMay cause diseaseOral contraceptivesNo increased riskOdds ratio 1.4AppendectomyProtectiveNot protectiveMonozygotic twins6% concordance58% concordanceDizygotic twins0% concordance4% concordancePATHOLOGY DistributionDiffuseSkip lesionsInflammationLimited to mucosaTransmuralPseudopoiypsMarkedNo to slightUlcersSuperficialDeep linearGranulomaNoYes (50%)Fistula/SinusesNoYesCLINICAL Gross blood in stoolYesOccasionallyMucusYesOccasionallySystemic symptomsOccasionallyFrequentlyPainOccasionallyFrequentlyAbdominal massRarelyYesSignificant perineal diseaseNoFrequentlyFistulasNoYesSmall-intestinal obstructionNoFrequentlyColonic obstructionRarelyFrequentlyResponse to antibioticsNoYesRecurrence after surgeryNoYesANCA-positiveFrequentlyRarelyASCA-positiveRarelyFrequentlyENDOSCOPIC Rectal sparingRarelyFrequentlyContinuous diseaseYesOccasionally"Cobblestoning"NoYesGranuloma on biopsyNoOccasionallyRADIOGRAPHIC Small bowelNoYessignificantly abnormal Abnormal terminal ileumOccasionallyYesSegmental colitisNoYesAsymmetric colitisNoYesStrictureOccasionallyFrequentlyNote: ANCA. antineutrophil cytoplasm antibody; ASCA, Anti-Sacchanomyces cerevisiae antibody.">