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A 22 year old male presents with complaints of dull lower back pain and morning stiffness. The pain was initially episodic, but now has become persistent and bilateral. On physical examination, there is tenderness over the costosternal junctions, spinous processes of the veebrae, and the iliac crests. Which of the following tests would be most likely to be helpful in establishing a diagnosis of ankylosing spondylitis?
C-reactive protein
Erythrocyte sedimentation rate
HLA typing
Serum alkaline phosphatase
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