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A 21 year old student is found to have hyperthyroidism. She is counselled on treatment options including radioactive iodine and antithyroid medications. Carbimazole acts on which part of the thyroid hormone synthesis pathway?
Cleavage of thyroglobulin by proteolysis
Coupling of monoiodotyrosine (MIT) and diiodotyrosine (DIT) forming triiodothyronine CTsl and thyroxine (T4)
Dehalogenation of iodinated tyrosine to recycle iodide
Organification of iodide by thyroid peroxidase incorporating tyrosine forming MIT and DIT
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