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Mrs. Katson 64-year-old obese woman with bilateral knee osteoahritis. She describes pain most days and limiting pain at least 2 days per week. She has tried activity modification (walking less) without success. All of the following therapies have been shown to be efficacious EXCEPT:
Acetaminophen
Glucocoicoid steroid intra-aicular injections
Glucosamine-chondroitin
Total joint ahroplasty
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