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Biochemistry
A 47-year-old male patient presents with painful ahritis in the right big toe and uric acid renal stones. He has been taking allopurinol for his condition. What biochemical defect would likely be found in this patient?
A defect in urea synthesis
An abnormality of the purine degradation pathway
An inability to synthesize non-essential amino acids
Defective topoisomerases
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