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Biochemistry
A 15 year old female patient presents with pain in the calf muscles on exercise. Routine investigation reveals burgundy-colored urine (sample obtained after exercise). Histopathology of mucle shows deposits of glycogen in an excess amount. Which of the following treatment modality should not be followed in this patient?
Avoidance of strenuous exercise
Glucose or sucrose given before exercise or injection of glucagon can markedly improve tolerance in these patients
Vitamin B6 supplementation
Specific enzyme replacement therapy (ERT) with recombinant human acid α-glucosidase
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