A 20-year-old woman with a family history of von Willebrand disease is found to have an activated paial thromboplastin time (aPTT) of 78 (normal = 32) on routine testing prior to cholecystectomy. Fuher investigation reveals a prothrombin time (PT) of 13 (normal = 12), a platelet count of 350,000/mm3 , and an abnormal bleeding time. Which of the following should be administered in the perioperative period?