Anaesthesia

All the following statements about Epinephrine used as an adjuvant are true Except

Extends block duration, limits systemic uptake, supplements analgesic effect, and acts as an indicator of intravascular injection

Can cause toxicity to peripheral nerves in patients with diabetes or chemotherapy

Local anaesthetics and epinephrine have no effect on peripheral nerve blood flow

Can aggravate local anaesthetic-induced neuraxial or peripheral nerve injury